Breast milk iodine and perchlorate concentrations in lactating Boston-area women.
نویسندگان
چکیده
CONTEXT Breastfed infants rely on adequate maternal dietary iodine intake. OBJECTIVE Our objective was to measure breast milk iodine and perchlorate, an inhibitor of iodide transport into the thyroid and potentially into breast milk, in Boston-area women. PARTICIPANTS The study included 57 lactating healthy volunteers in the Boston area. MEASUREMENTS Breast milk iodine and perchlorate concentrations and urine iodine, perchlorate, and cotinine concentrations were measured. For comparison, iodine and perchlorate levels in infant formulae were also measured. RESULTS Median breast milk iodine content in 57 samples was 155 microg/liter (range, 2.7-1968 microg/liter). Median urine iodine was 114 microg/liter (range, 25-920 microg/liter). Perchlorate was detectable in all 49 breast milk samples (range, 1.3-411 microg/liter), all 56 urine samples (range, 0.37-127 microg/liter), and all 17 infant formula samples (range, 0.22-4.1 microg/liter) measured. Breast milk iodine content was significantly correlated with urinary iodine per gram creatinine and urinary cotinine but was not significantly correlated with breast milk or urinary perchlorate. CONCLUSIONS Perchlorate exposure was not significantly correlated with breast milk iodine concentrations. Perchlorate was detectable in infant formula but at lower levels than in breast milk. Forty-seven percent of women sampled may have been providing breast milk with insufficient iodine to meet infants' requirements.
منابع مشابه
Perchlorate, iodine supplements, iodized salt and breast milk iodine content.
This study was undertaken to determine if increasing maternal iodine intake through single dose tablets will decrease breast milk concentrations of the iodine-uptake inhibitor, perchlorate, through competitive inhibition. We also sought to determine if the timing of supplementation influences the fraction of iodine excreted in milk versus urine and to compare the effectiveness of iodized salt a...
متن کاملIodine nutrition of pregnant and lactating women in Hong Kong, where intake is of borderline sufficiency.
OBJECTIVE To describe the iodine nutrition of pregnant and lactating women in Hong Kong, where intake is of borderline sufficiency. DESIGN Review of cross-sectional and prospective studies. SETTING China, Hong Kong Special Administrative Region (SAR). SUBJECTS Pregnant and lactating women. RESULTS Studies of pregnant women in Hong Kong SAR have revealed an increase in the urinary iodine...
متن کاملAn assessment of urinary and breast milk iodine concentrations in lactating mothers from Gorgan, Iran, 2003.
Dietary iodine is essential for the production of thyroid hormones. Breast-fed infants are reliant on maternal iodine intake. The aim of this study was to evaluate iodine sufficiency in lactating women in Iran. The sample consisted of 100 lactating mothers referred to the Taleghani Hospital of Gorgan, Iran. Goiter was graded according to World Health Organization (WHO) classification. Spot urin...
متن کاملتوزیع ید در ادرار و شیر مادران در دوران پس از زایمان در گرگان ، سال 1382
Background : are reliant on adequate maternal iodine intake. The aim of this study was to evaluate iodine sufficiency in lactating women in Iran . Materials and methods referred to the Taleghani Hospital of Gorgan between April and June 2003. Subjects were within the 1 st -6 th month of their postpartum period. Goiter was graded according to WHO classification. Spot urine ( 2-3 ml) and breast...
متن کاملSuboptimal Iodine Concentration in Breastmilk and Inadequate Iodine Intake among Lactating Women in Norway
Breastfed infants depend on sufficient maternal iodine intake for optimal growth and neurological development. Despite this, few studies have assessed iodine concentrations in human milk and there is currently no published data on iodine status among lactating women in Norway. The aim of this study was to assess iodine concentrations in breast milk (BMIC) in lactating women and estimate iodine ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of clinical endocrinology and metabolism
دوره 92 5 شماره
صفحات -
تاریخ انتشار 2007